Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000088)
Formula
SVG example
Reactant Adenylylsulfate Product ATP
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000089 Adenylylsulfate PAPS Unclear Adenylylsulfate [1]
MR000091 Adenylylsulfate Pi Unclear Adenylylsulfate [1]
MR000090 Adenylylsulfate Sulfite Reduction - Reduction Adenylylsulfate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000084 Adenosine-c-phosphate ATP Unclear Adenosine-c-phosphate [2]
MR000073 ADP ATP Other reaction - Phosphorylation Adenosine [3], [4]
MR004266 AMP ATP Unclear Methylthioadenosine [5]
MR004029 AMP ATP Unclear Xanthine [6]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000075 ATP ADP Other reaction - Dephosphorylation Adenosine [3], [4]
MR000074 ATP AMP Other reaction - Dephosphorylation Adenosine [3], [4]
References
1 Adenosine-5'-phosphosulfate--a multifaceted modulator of bifunctional 3'-phospho-adenosine-5'-phosphosulfate synthases and related enzymes FEBS J. 2013 Jul;280(13):3050-7. doi: 10.1111/febs.12252.
2 Transport and metabolism of N6- and C8-substituted analogs of adenosine 3',5'-cyclic monophosphate and adenosine 3'5'-cyclic phosphorothioate by the isolated perfused rat kidney Life Sci. 1983 Mar 28;32(13):1489-98. doi: 10.1016/0024-3205(83)90915-3.
3 Adenosine Metabolism: Emerging Concepts for Cancer Therapy Cancer Cell. 2019 Dec 9;36(6):582-596. doi: 10.1016/j.ccell.2019.10.007.
4 Purine signaling pathway dysfunction in autism spectrum disorders: Evidence from multiple omics data. Front Mol Neurosci. 2023 Feb 3;16:1089871. doi: 10.3389/fnmol.2023.1089871.
5 Targeting tumors that lack methylthioadenosine phosphorylase (MTAP) activity: current strategies
6 Xanthine metabolism in Bacillus subtilis: characterization of the xpt-pbuX operon and evidence for purine- and nitrogen-controlled expression of genes involved in xanthine salvage and catabolism

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