Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000273)
Formula Reactant Apremilast metabolite M5 Product Apremilast metabolite M19
Reactant Info Product Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000280 Apremilast Apremilast metabolite M5 Unclear Apremilast [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000275 Apremilast metabolite M5 Apremilast metabolite M13 Conjugation - Glucuronidation Apremilast [1]
MR000274 Apremilast metabolite M5 Apremilast metabolite M22 Hydrolysis - Hydrolysis Apremilast [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000259 O-desmethyl Apremilast Apremilast metabolite M19 Oxidation - O-Demethylation Apremilast [1]
References
1 Disposition, metabolism and mass balance of [(14)C]apremilast following oral administration. Xenobiotica. 2011 Dec;41(12):1063-75.

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