Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000282)
Formula Reactant Arbekacin Product 2'-N-acetyl ABK
Reactant Info Product Info
Metabolic Enzyme Aminoglycoside acetyltransferase (aac) DME Info
Metabolic Type Conjugation - N-Acetylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000283 Arbekacin 3"-N-Acetylarbekacin Conjugation - 3"-N-Acetylation Arbekacin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000281 2'-N-acetyl ABK 2',6'-di-N-acetyl ABK Unclear Arbekacin [2]
References
1 The novel enzymatic 3''-N-acetylation of arbekacin by an aminoglycoside 3-N-acetyltransferase of Streptomyces origin and the resulting activity. J Antibiot (Tokyo). 1998 Aug;51(8):735-42.
2 Enzymatic 2'-N-acetylation of arbekacin and antibiotic activity of its product J Antibiot (Tokyo). 1996 May;49(5):458-64. doi: 10.7164/antibiotics.49.458.

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