Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000475)
Formula Reactant 4'-OH-bupivacaine Product 4'-OH-bupivacaine glucuronide
Reactant Info Product Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000478 Bupivacaine hydrochloride 4'-OH-bupivacaine Oxidation - Hydroxylation Bupivacaine hydrochloride [1]
References
1 Oxidative metabolism of bupivacaine into pipecolylxylidine in humans is mainly catalyzed by CYP3A. Drug Metab Dispos. 2000 Apr;28(4):383-5.

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