Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000580)
Formula
SVG example
Reactant Desacetyl-cefotaxime Product Deacetylcefotaxime lactone
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000583 Cefotaxime Desacetyl-cefotaxime Oxidation - Deacetylation Cefotaxime [1], [2]
MR011857 Ro-23-9424 Desacetylcefotaxime Unclear - Unclear Ro-23-9424 [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000581 Deacetylcefotaxime lactone Desacetylcefotaxime lactone M2 Unclear Cefotaxime [1]
MR000582 Deacetylcefotaxime lactone Desacetylcefotaxime lactone M3 Unclear Cefotaxime [1]
References
1 Metabolism of cefotaxime in animals and humans Rev Infect Dis. 1982 Sep-Oct;4 Suppl:S325-32. doi: 10.1093/clinids/4.supplement_2.s325.
2 Molecularly Imprinted Polymers as Solid-Phase Microextraction Fibers for the Isolation of Selected Antibiotics from Human Plasma. Materials (Basel). 2021 Aug 27;14(17):4886. doi: 10.3390/ma14174886.
3 Pharmacokinetics of Ro 23-9424, a dual-action cephalosporin, in animals

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