Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000660)
Formula
	Reactant	Cimetidine	Product	Hydroxymethyl cimetidine
	Reactant	Reactant Info	Product	Product Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR000659	Cimetidine	Cimetidine sulfoxide metabolite	Oxidation - 6-Hydroxylation	Cimetidine	[1], [2]

References
1	Cimetidine sulfoxidation in small intestinal microsomes Drug Metab Dispos. 1998 Sep;26(9):940-2.
2	An improved high performance liquid chromatographic method for determination of cimetidine and its major metabolite in plasma Arch Invest Med (Mex). 1989 Oct-Dec;20(4):309-13.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.