Details of the Metabolic Reaction (MR)
General Information of This Metabolic Reaction (MR) (ID: MR000716) | ||||||
---|---|---|---|---|---|---|
Formula |
CYP2C9
...
O-Demethylation
|
|||||
Reactant | Dacomitinib | Product | PF-05199265 | |||
Reactant Info | Product Info | |||||
Metabolic Enzyme | Cytochrome P450 2C9 (CYP2C9) | DME Info | ||||
Cytochrome P450 2D6 (CYP2D6) | DME Info | |||||
Metabolic Type | Oxidation - O-Demethylation | |||||
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