Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000730)
Formula	Oxidation
	Reactant	Dapsone hydroxylamine	Product	Nitroso-dapsone
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Oxidation - Oxidation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR000733	Dapsone	Dapsone hydroxylamine	Oxidation - N-Hydroxylation	Dapsone	[1]

Other MR(s) Related to The Product of This MR

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR000731	Nitroso-dapsone	Dapsone mercaptal intermediate	Conjugation - Glutathione Conjugation	Dapsone	[1]

References
1	Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.