Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000837)
Formula
CYP
SVG example
Hydroxylation
Reactant Diflunisal Product 3-hydroxy-diflunisal
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 (CYP) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000838 Diflunisal Diflunisal acyl glucuronide Conjugation - Glucuronidation Diflunisal [1], [2]
References
1 Differential effects of phenobarbital on ester and ether glucuronidation of diflunisal in rats. J Pharmacol Exp Ther. 1987 Sep;242(3):1013-8.
2 Identification of a hydroxy metabolite of diflunisal in rat and human urine Xenobiotica. 1991 Nov;21(11):1521-33. doi: 10.3109/00498259109044402.

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