Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000856)
Formula
cgr1 ...
SVG example
Reduction
Reactant Digoxin Product Dihydrodigoxin
Reactant Info Product Info
Metabolic Enzyme Cardiac glycoside reductase 1 (cgr1) DME Info
Cardiac glycoside reductase 2 (cgr2) DME Info
Metabolic Type Reduction - Reduction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000855 Digoxin Digoxigenin-bisdigitoxoside Oxidation - Cleavage Digoxin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000852 Dihydrodigoxin Dihydrodigoxigenin-bisdigitoxoside Oxidation - Cleavage Digoxin [2]
References
1 Metabolism of digoxin and digoxigenin digitoxosides in rat liver microsomes: involvement of cytochrome P4503A Xenobiotica. 1999 Feb;29(2):171-85. doi: 10.1080/004982599238722.
2 American Society of Health System Pharmacists; AHFS Drug Information 2010. Bethesda, MD. (2010), p. 2511

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.