General Information of This Metabolic Reaction (MR) (ID: MR000902)
Formula Reactant Efavirenz metabolite M5 Product Efavirenz metabolite M7
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronyltransferase (UGT) DME Info
Metabolic Type Conjugation - Conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000904 Efavirenz Efavirenz metabolite M5 Oxidation - Hydroxylation Efavirenz [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000901 Efavirenz metabolite M5 Efavirenz metabolite M6 Conjugation - Conjugation Efavirenz [1]
References
1 Clinical pharmacokinetics and drug-drug interactions of Elbasvir/Grazoprevir. Eur J Drug Metab Pharmacokinet. 2018 Oct;43(5):509-531.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.