Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000907)
Formula Reactant Eltrombopag olamine Product Eltrombopag olamine glucuronide conjugate
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A1 (UGT1A1) DME Info
UDP-glucuronosyltransferase 1A3 (UGT1A3) DME Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000906 Eltrombopag olamine Mono-oxygenation Oxidation - Oxidation Eltrombopag olamine [1]
References
1 Eltrombopag for use in children with immune thrombocytopenia. Blood Adv. 2018 Feb 27;2(4):454-461.

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