Details of the Drug Metabolite (DM)

General Information of Drug Metabolite (DM) (ID: DM000574)
DM Name	Mono-oxygenation

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 1A2 (CYP1A2)	DME0003	Eltrombopag olamine	Oxidation - Oxidation	Eltrombopag olamine	[1]
Cytochrome P450 2C8 (CYP2C8)	DME0018	Eltrombopag olamine	Oxidation - Oxidation	Eltrombopag olamine	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Eltrombopag olamine		DR0569	Approved		Thrombocytopenia

References
1	Eltrombopag for use in children with immune thrombocytopenia. Blood Adv. 2018 Feb 27;2(4):454-461.

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