Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001008)
Formula Reactant Ezetimibe Product Ezetimibe-glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A1 (UGT1A1) DME Info
UDP-glucuronosyltransferase 1A3 (UGT1A3) DME Info
UDP-glucuronosyltransferase 2B7 (UGT2B7) DME Info
UDP-glucuronosyltransferase 2B15 (UGT2B15) DME Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001009 Ezetimibe Benzylic glucuronide SCH 488128 Oxidation - Oxidation Ezetimibe [1]
MR001007 Ezetimibe SCH 57871 Conjugation - Glucuronidation Ezetimibe [1]
References
1 Ezetimibe: a review of its metabolism, pharmacokinetics and drug interactions. Clin Pharmacokinet. 2005;44(5):467-94.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.