Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001031)
Formula Reactant Omega-hydroxyfinasteride Product Hydroxyfinasteride glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A4 (UGT1A4) DME Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001035 Finasteride Omega-hydroxyfinasteride Oxidation - Hydroxylation Finasteride [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001030 Omega-hydroxyfinasteride Omega-aldehyde finasteride Oxidation - Oxidation Finasteride [1]
References
1 Finasteride for hair loss: a review J Dermatolog Treat. 2022 Jun;33(4):1938-1946. doi: 10.1080/09546634.2021.1959506.
2 LABEL:FINASTERIDE tablet

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