Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001035)
Formula
SVG example
Hydroxylation
Reactant Finasteride Product Omega-hydroxyfinasteride
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001038 Finasteride . Unclear Finasteride [1]
MR001036 Finasteride 6alpha-hydroxyfinasteride Oxidation - Oxidation Finasteride [2]
MR001037 Finasteride Finasteride monocarboxylic acid metabolite Oxidation - Oxidation Finasteride [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001031 Omega-hydroxyfinasteride Hydroxyfinasteride glucuronide Conjugation - Glucuronidation Finasteride [2]
MR001030 Omega-hydroxyfinasteride Omega-aldehyde finasteride Oxidation - Oxidation Finasteride [2]
References
1 Drug Interactions Flockhart Table:Docetaxel
2 Finasteride for hair loss: a review J Dermatolog Treat. 2022 Jun;33(4):1938-1946. doi: 10.1080/09546634.2021.1959506.
3 LABEL:FINASTERIDE tablet

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