Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001080)
Formula
SVG example
Reactant Tetrahydrofolic acid Product 5,10-methylene tetrahydrofolate (THF)
Reactant Info Product Info
Metabolic Enzyme Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (MTHFD2) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001084 Folic acid Tetrahydrofolic acid Reduction - Reduction Folic acid [1]
MR001502 Levomefolic acid Tetrahydrofolic acid Unclear Levomefolic acid [2], [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001081 5,10-methylene tetrahydrofolate (THF) 5-Methyltetrahydrofolate Unclear Folic acid [1]
References
1 DrugBank(Pharmacology-Metabolism)Folic acid
2 Folic acid and L-5-methyltetrahydrofolate: comparison of clinical pharmacokinetics and pharmacodynamics. Clin Pharmacokinet. 2010 Aug;49(8):535-48.
3 DrugBank(Pharmacology-Metabolism)Levomefolic acid

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