Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001081)
Formula
SVG example
Reactant 5,10-methylene tetrahydrofolate (THF) Product 5-Methyltetrahydrofolate
Reactant Info Product Info
Metabolic Enzyme Methylenetetrahydrofolate reductase (MTHFR) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001080 Tetrahydrofolic acid 5,10-methylene tetrahydrofolate (THF) Unclear Folic acid [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008762 5,10-methylenetetrahydrofolate 5-Methyltetrahydrofolate Unclear - Unclear Leucovorin Calcium [2]
MR008767 5,10-methylenetetrahydrofolate 5-Methyltetrahydrofolate Unclear - Unclear Leucovorin [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001082 5-Methyltetrahydrofolate Methionine Unclear Folic acid [1]
MR008763 5-Methyltetrahydrofolate Tetrahydrofolate Unclear - Unclear Leucovorin Calcium [2]
MR008768 5-Methyltetrahydrofolate Tetrahydrofolate Unclear - Unclear Leucovorin [2]
References
1 DrugBank(Pharmacology-Metabolism)Folic acid
2 Disposition of leucovorin and its metabolites in dietary folic acid-deplete mice - comparison between tumor, liver, and plasma

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