Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001091)
Formula Reactant R529 Product R529 O-glucuronide metabolite
Reactant Info Product Info
Metabolic Type Conjugation - O-Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001087 R406 R529 Unclear Fostamatinib [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001089 R529 3,5 benzene diol metabolite of R406 Oxidation - Oxidation Fostamatinib [2]
MR001090 R529 R529 Sulfate-conjugate metabolite Conjugation - Sulfation Fostamatinib [1]
References
1 DrugBank(Pharmacology-Metabolism)Fostamatinib
2 Clinical Pharmacokinetics and Pharmacodynamics of Fostamatinib and Its Active Moiety R406 Clin Pharmacokinet. 2022 Jul;61(7):955-972. doi: 10.1007/s40262-022-01135-0.

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