Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001098)
Formula
SVG example
N-Dealkylation
Reactant Furosemide Product 4-chloro-5-sulfamoylanthranilic acid
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2E1 (CYP2E1) DME Info
Metabolic Type Oxidation - N-Dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001099 Furosemide Furosemide glucuronide Conjugation - Glucuronidation Furosemide [1]
References
1 High-performance liquid chromatographic determination and identification of acyl migration and photodegradation products of furosemide 1-O-acyl glucuronide J Chromatogr B Biomed Sci Appl. 1998 Oct 23;718(1):153-62. doi: 10.1016/s0378-4347(98)00357-0.

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