Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001108)
Formula
SVG example
Glucuronidation
Reactant O-desmethyl-galantamine Product O-desmethyl-galantamine glucuronide metabolite
Reactant Info Product Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001110 Galantamine hydrobromide O-desmethyl-galantamine Oxidation - O-Demethylation Galantamine hydrobromide [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001107 O-desmethyl-galantamine Sulfate conjugate of O-desmethyl-galantamine Conjugation - Sulfation Galantamine hydrobromide [3]
References
1 The metabolism and excretion of galantamine in rats, dogs, and humans Drug Metab Dispos. 2002 May;30(5):553-63. doi: 10.1124/dmd.30.5.553.
2 Clinical pharmacokinetics of galantamine. Clin Pharmacokinet. 2003;42(15):1383-92.
3 DrugBank(Pharmacology-Metabolism)Galantamine hydrobromide

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