Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001138)
Formula
SVG example
Reactant Glasdegib Product Glasdegib metabolite M2
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001134 Glasdegib Glasdegib metabolite M1,9 Oxidation - Oxidation Glasdegib [1]
MR001136 Glasdegib Glasdegib metabolite M11 Oxidation - Oxidation Glasdegib [1]
MR001132 Glasdegib Glasdegib metabolite M3 Oxidation - Demethylation Glasdegib [1]
MR001137 Glasdegib Glasdegib metabolite M4 Oxidation - Oxidation Glasdegib [1]
MR001135 Glasdegib Glasdegib metabolite M6 Oxidation - Glucuronidation; Oxidation Glasdegib [1]
MR001133 Glasdegib Glasdegib metabolite M8 Conjugation - Glucuronidation Glasdegib [1]
References
1 Metabolism, excretion and pharmacokinetics of [14C]glasdegib (PF-04449913) in healthy volunteers following oral administration. Xenobiotica. 2017 Dec;47(12):1064-1076.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.