Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR001139)
Formula	Oxidation
	Reactant	Cyclohexyl hydroxymethyl glimepiride		Product	Cyclohexyl carboxyl glimepiride
	Reactant	Reactant Info		Product	Product Info
Metabolic Type	Oxidation - Oxidation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR001140	Glimepiride	Cyclohexyl hydroxymethyl glimepiride	Oxidation - Hydroxylation	Glimepiride	[1], [2]

References
1	Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
2	Simultaneous determination of glimepiride and its metabolites in human plasma by liquid chromatography coupled to a tandem mass spectrometry Arch Pharm Res. 2011 Dec;34(12):2073-8. doi: 10.1007/s12272-011-1210-0.

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