Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001408)
Formula
Ks
SVG example
Phosphorylation
Reactant Lamivudine Product Lamivudine monophosphate
Reactant Info Product Info
Metabolic Enzyme Kinase (Ks) DME Info
Metabolic Type Other reaction - Phosphorylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001409 Lamivudine Lamivudine sulfoxide Unclear lamivudine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001407 Lamivudine metabolite M Lamivudine monophosphate Unclear lamivudine [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001404 Lamivudine monophosphate Lamivudine diphosphate Other reaction - Phosphorylation lamivudine [2], [3]
References
1 Pharmacogenomics knowledge for personalized medicine Clin Pharmacol Ther. 2012 Oct;92(4):414-7. doi: 10.1038/clpt.2012.96.
2 Model for intracellular Lamivudine metabolism in peripheral blood mononuclear cells ex vivo and in human immunodeficiency virus type 1-infected adolescents. Antimicrob Agents Chemother. 2006 Aug;50(8):2686-94.
3 Antiviral and cellular metabolism interactions between Dexelvucitabine and lamivudine Antimicrob Agents Chemother. 2007 Jun;51(6):2130-5. doi: 10.1128/AAC.01543-06.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.