General Information of This Metabolic Reaction (MR) (ID: MR001409)
Formula
Reactant Lamivudine Product Lamivudine sulfoxide
Reactant Info Product Info
Metabolic Enzyme Sulfotransferase 1B1 (SULT1B1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001408 Lamivudine Lamivudine monophosphate Other reaction - Phosphorylation lamivudine [1], [2]
References
1 Model for intracellular Lamivudine metabolism in peripheral blood mononuclear cells ex vivo and in human immunodeficiency virus type 1-infected adolescents. Antimicrob Agents Chemother. 2006 Aug;50(8):2686-94.
2 Antiviral and cellular metabolism interactions between Dexelvucitabine and lamivudine Antimicrob Agents Chemother. 2007 Jun;51(6):2130-5. doi: 10.1128/AAC.01543-06.

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