Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001526)
Formula
SVG example
Reactant 1-pyrroline-5-carboxylic acid Product L-Proline
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007605 Proline Delta-1-pyrroline-5-carboxylic acid Oxidation - Oxidationn Proline [1]
MR001521 L-glutamate 1-pyrroline-5-carboxylic acid Unclear L-glutamine [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007606 Delta-1-pyrroline-5-carboxylic acid Glutamate Unclear Proline [1]
MR007607 Delta-1-pyrroline-5-carboxylic acid Ornithine Unclear Proline [1]
MR001524 1-pyrroline-5-carboxylic acid L-citrulline Unclear L-glutamine [2]
MR001525 1-pyrroline-5-carboxylic acid L-Ornithine Unclear L-glutamine [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003202 Pyr2C L-proline Unclear AK-41099 [3]
MR012747 L-A1Pyrroline-5-carboxylate L-Proline Unclear - Unclear Arginine [4]
References
1 Proline metabolism in cancer
2 The Emerging Role of l-Glutamine in Cardiovascular Health and Disease Nutrients. 2019 Sep 4;11(9):2092. doi: 10.3390/nu11092092.
3 Structure of Thermococcus litoralis trans-3-hydroxy-l-proline dehydratase in the free and substrate-complexed form. Biochem Biophys Res Commun. 2019 Aug 13;516(1):189-195.
4 Arginine Metabolism Revisited

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