Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR001613)
Formula	cyp102A1 Hydroxylation
	Reactant	Meclofenamic acid		Product	3-hydroxymethyl Mefenamic Acid
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	Cytochrome P450 102A1 (cyp102)					DME Info
Metabolic Type	Oxidation - Hydroxylation

Other MR(s) Related to The Product of This MR

Other MR(s) That Produce The Product of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR001630	Mefenamic acid	3-hydroxymethyl Mefenamic Acid	Oxidation - Hydroxylation	Mefenamic acid	[1]

References
1	Cytochrome P450-mediated bioactivation of mefenamic acid to quinoneimine intermediates and inactivation by human glutathione S-transferases. Chem Res Toxicol. 2014 Dec 15;27(12):2071-81.

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