Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001659)
Formula Reactant 4-amino-antipyrine (AA) Product Arachidonoyl-4-aminoantipyrine (ARA-4-AA)
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001655 N-Desmethylaminopyrine 4-amino-antipyrine (AA) Oxidation - N-Demethylation Metamizole sodium [1], [2]
MR001657 4-formyl-amino-antipyrine (FAA) 4-amino-antipyrine (AA) Oxidation - N-Demethylation Metamizole sodium [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001658 4-amino-antipyrine (AA) 4-acetyl-amino-antipyrine (AAA) Conjugation - Acetylation Metamizole sodium [1], [2]
References
1 Metamizole (Dipyrone) and the Liver: A Review of the Literature J Clin Pharmacol. 2019 Nov;59(11):1433-1442. doi: 10.1002/jcph.1512.
2 Clinical pharmacokinetics of dipyrone and its metabolites Clin Pharmacokinet. 1995 Mar;28(3):216-34. doi: 10.2165/00003088-199528030-00004.

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