Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001723)
Formula Reactant Neratinib metabolite M8 Product Neratinib metabolite M4,M5
Reactant Info Product Info
Metabolic Type Conjugation - Glutathione Conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001725 Neratinib Neratinib metabolite M8 Oxidation - Oxygenation Neratinib [1]
References
1 Metabolic profiles of neratinib in rat by using ultra-high-performance liquid chromatography coupled with diode array detector and Q-Exactive Orbitrap tandem mass spectrometry Biomed Chromatogr. 2018 May 3:e4272. doi: 10.1002/bmc.4272.

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