Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001753)
Formula
SVG example
Chain Hydroxylation
Reactant Nisoldipine metabolite M10 Product Nisoldipine metabolite M4
Reactant Info Product Info
Metabolic Type Oxidation - Chain Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001756 Nisoldipine metabolite M13 Nisoldipine metabolite M10 Unclear Nisoldipine [1]
MR001752 Nisoldipine metabolite M9 Nisoldipine metabolite M10 Oxidation - Dehydrogenation Nisoldipine [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001754 Nisoldipine metabolite M4 Nisoldipine metabolite M5 Oxidation - Chain Hydroxylation Nisoldipine [1]
References
1 Clinical pharmacokinetics of nisoldipine coat-core Clin Pharmacokinet. 1998 Sep;35(3):191-208. doi: 10.2165/00003088-199835030-00003.
2 U. S. FDA Label -Nisoldipine

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