Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001752)
Formula
SVG example
Dehydrogenation
Reactant Nisoldipine metabolite M9 Product Nisoldipine metabolite M10
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Dehydrogenation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001759 Nisoldipine Nisoldipine metabolite M9 Unclear Nisoldipine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001756 Nisoldipine metabolite M13 Nisoldipine metabolite M10 Unclear Nisoldipine [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001753 Nisoldipine metabolite M10 Nisoldipine metabolite M4 Oxidation - Chain Hydroxylation Nisoldipine [1]
References
1 Clinical pharmacokinetics of nisoldipine coat-core Clin Pharmacokinet. 1998 Sep;35(3):191-208. doi: 10.2165/00003088-199835030-00003.

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