Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001940)
Formula
SVG example
Reduction
Reactant Pantoprazole Sodium Product Pantoprazole Sulfone
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Reduction - Reduction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001938 Pantoprazole Sodium Desmethylpantoprazole Oxidation - Demethylation Pantoprazole Sodium [1]
MR001939 Pantoprazole Sodium Pantoprazole sulfate Conjugation - Sulfation Pantoprazole Sodium [2]
References
1 Proton pump inhibitors: from CYP2C19 pharmacogenetics to precision medicine. Expert Opin Drug Metab Toxicol. 2018 Apr;14(4):447-460.
2 Interaction of proton pump inhibitors with cytochromes P450: consequences for drug interactions. Yale J Biol Med. 1996 May-Jun;69(3):203-9.

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