General Information of This Metabolic Reaction (MR) (ID: MR001975)
Formula
SVG example
Penultimate Oxidation
Reactant Pentobarbital Product 3'-hydroxypentobarbital
Reactant Info Product Info
Metabolic Type Oxidation - Penultimate Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001974 Pentobarbital 4-hydroxyphenobarbital Oxidation - Hydroxylation Pentobarbital [1]
MR001977 Pentobarbital Pentobarbital carboxylic acid Oxidation - Oxidation Pentobarbital [1]
MR001976 Pentobarbital Phenobarbitone glucoside Conjugation - Glucuronidation Pentobarbital [1]
References
1 CYP2C19 polymorphism effect on phenobarbitone. Pharmacokinetics in Japanese patients with epilepsy: analysis by population pharmacokinetics. Eur J Clin Pharmacol. 2000 Feb-Mar;55(11-12):821-5.

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