Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR001976)
Formula	Glucuronidation
	Reactant	Pentobarbital		Product	Phenobarbitone glucoside
	Reactant	Reactant Info		Product	Product Info
Metabolic Type	Conjugation - Glucuronidation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR001975	Pentobarbital	3'-hydroxypentobarbital	Oxidation - Penultimate Oxidation	Pentobarbital	[1]
MR001974	Pentobarbital	4-hydroxyphenobarbital	Oxidation - Hydroxylation	Pentobarbital	[2]
MR001977	Pentobarbital	Pentobarbital carboxylic acid	Oxidation - Oxidation	Pentobarbital	[2]

References
1	American Society of Health System Pharmacists; AHFS Drug Information 2009. Bethesda, MD. (2009), p. 2666
2	CYP2C19 polymorphism effect on phenobarbitone. Pharmacokinetics in Japanese patients with epilepsy: analysis by population pharmacokinetics. Eur J Clin Pharmacol. 2000 Feb-Mar;55(11-12):821-5.

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