Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002011)
Formula
SVG example
O-Deethylation
Reactant Phenacetin Product Acetaminophen
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Metabolic Type Oxidation - O-Deethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002010 Phenacetin N-OH-phenacetin Oxidation - N-Oxidation Phenacetin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000121 Alfentanil metabolite AM5 Alfentanil metabolite AM3 Hydrolysis - Amid Hydrolysis; Acetylation Alfentanil [2]
References
1 DrugBank(Pharmacology-Metabolism)Phenacetin
2 Alfentanil pharmacokinetics and metabolism in humans Anesthesiology. 1988 Oct;69(4):527-34. doi: 10.1097/00000542-198810000-00012.

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