Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002106)
Formula
SVG example
Hydroxylation
Reactant Prazepam Product 3-hydroxyprazepam
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002107 Prazepam Nordazepam Oxidation - N-Dealkylation Prazepam [1], [2], [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002104 3-hydroxyprazepam Oxazepam Oxidation - N-Dealkylation Prazepam [2], [3]
References
1 Metabolic profile of oxazepam and related benzodiazepines: clinical and forensic aspects. Drug Metab Rev. 2017 Nov;49(4):451-463.
2 Prazepam metabolism by man Clin Pharmacol Ther. 1970 Nov-Dec;11(6):890-7. doi: 10.1002/cpt1970116890.
3 Prazepam metabolites in dog urine J Pharm Sci. 1970 Mar;59(3):322-5. doi: 10.1002/jps.2600590309.

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