Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002219)
Formula Reactant Salbutamol Product Salbutamol Oxidative metabolites
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Oxidative Deamination
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002218 Salbutamol Rac albuterol-4-sulfate Unclear Salbutamol [1]
MR002220 Salbutamol Salbutamol Glucuronic acid conjugates Conjugation - Conjugation Salbutamol [2]
References
1 SULT 1A3 single-nucleotide polymorphism and the single dose pharmacokinetics of inhaled salbutamol enantiomers: are some athletes at risk of higher urine levels? Drug Test Anal. 2015 Feb;7(2):109-13.
2 Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metab Rev. 2002 Feb-May;34(1-2):83-448.

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