Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002241)
Formula
DPP4 ...
SVG example
Hydrolysis; Oxidation
Reactant Semaglutide Product U7 semaglutide
Reactant Info Product Info
Metabolic Enzyme Dipeptidyl peptidase IV (DPP4) DME Info
Neprilysin (MME) DME Info
Metabolic Type Oxidation - Hydrolysis; Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002243 Semaglutide . Hydrolysis - Hydrolysis Semaglutide [1]
MR002242 Semaglutide P3 semaglutide Oxidation - Hydrolysis; Oxidation Semaglutide [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002240 U7 semaglutide U6 semaglutide Hydrolysis - Hydrolysis Semaglutide [1]
References
1 Absorption, metabolism and excretion of the GLP-1 analogue semaglutide in humans and nonclinical species. Eur J Pharm Sci. 2017 Jun 15;104:31-41.

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