Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002293)
Formula Reactant Sulfapyridine Product OH-sulfapyridine
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002285 Sulfapyridine N-acetylsufapyridine Conjugation - Acetylation Sulfapyridine [1]
MR002287 Sulfapyridine Sulfapyridine glucuronide Conjugation - Glucuronidation Sulfapyridine [2]
MR002292 Sulfapyridine N-acetylsufapyridine Conjugation - Acetylation Sulfasalazine [1]
MR002294 Sulfapyridine Sulfapyridine glucuronide Conjugation - Glucuronidation Sulfasalazine [2]
References
1 Effects of NAT2 polymorphism on SASP pharmacokinetics in Chinese population. Clin Chim Acta. 2009 Sep;407(1-2):30-5.
2 Small bowel absorption of sulfasalazine and its hepatic metabolism in human beings, cats, and rats Gastroenterology. 1979 Aug;77(2):280-4.

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