Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002312)
Formula Reactant Suvorexant metabolite M10a Product Suvorexant metabolite M12
Reactant Info Product Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002315 Suvorexant Suvorexant metabolite M10a Oxidation - Hydoxylation Suvorexant [1], [2]
References
1 CYP450-Mediated metabolism of suvorexant and investigation of metabolites in forensic case specimens Forensic Sci Int. 2020 Jul;312:110307. doi: 10.1016/j.forsciint.2020.110307.
2 In vitro and in vivo characterisation of the metabolism and disposition of suvorexant in humans Xenobiotica. 2016 Oct;46(10):882-95. doi: 10.3109/00498254.2015.1129565.

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