General Information of This Metabolic Reaction (MR) (ID: MR002440)
Formula
SVG example
Glutathione Conjugation
Reactant 4'-hydroxytrazodone Product Trazodone hydrochloride M6
Reactant Info Product Info
Metabolic Type Conjugation - Glutathione Conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002443 Trazodone hydrochloride 4'-hydroxytrazodone Oxidation - Hydroxylation Trazodone hydrochloride [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002441 4'-hydroxytrazodone Trazodone hydrochloride MW Unclear Trazodone hydrochloride [1]
References
1 Metabolic activation of the nontricyclic antidepressant trazodone to electrophilic quinone-imine and epoxide intermediates in human liver microsomes and recombinant P4503A4. Chem Biol Interact. 2005 Jun 30;155(1-2):10-20.

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