Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002440)
Formula	Glutathione Conjugation
	Reactant	4'-hydroxytrazodone	Product	Trazodone hydrochloride M6
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Conjugation - Glutathione Conjugation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR002443	Trazodone hydrochloride	4'-hydroxytrazodone	Oxidation - Hydroxylation	Trazodone hydrochloride	[1]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR002441	4'-hydroxytrazodone	Trazodone hydrochloride MW	Unclear	Trazodone hydrochloride	[1]

References
1	Metabolic activation of the nontricyclic antidepressant trazodone to electrophilic quinone-imine and epoxide intermediates in human liver microsomes and recombinant P4503A4. Chem Biol Interact. 2005 Jun 30;155(1-2):10-20.

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