Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002463)
Formula
SVG example
Hydroxylation
Reactant Trimipramine Product 2-hydroxytrimipramine
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002462 Trimipramine Desmethyltrimipramine Oxidation - Demethylation Trimipramine [1], [2]
References
1 Nonlinear kinetics of trimipramine in depressed patients J Clin Pharmacol. 1989 Aug;29(8):746-7. doi: 10.1002/j.1552-4604.1989.tb03410.x.
2 Determination of trimipramine and metabolites in plasma by liquid chromatography with electrochemical detection J Pharm Sci. 1984 Dec;73(12):1745-8. doi: 10.1002/jps.2600731221.

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