Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002562)
Formula Reactant RP56976 Product RPR104952
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002566 RPR112698 RP56976 Oxidation - 10-O-Demethylation Cabazitaxel [1]
MR002561 RPR123142 RP56976 Oxidation - 7-O-Demethylation Cabazitaxel [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002568 Cabazitaxel metabolite M07 RPR104952 Oxidation - 10-O-Demethylation Cabazitaxel [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002563 RPR104952 RPR111026 Oxidation - Hydroxylation Cabazitaxel [1]
References
1 A phase I open-label study investigating the disposition of [14C]-cabazitaxel in patients with advanced solid tumors Anticancer Drugs. 2015 Mar;26(3):350-8. doi: 10.1097/CAD.0000000000000185.

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