Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002563)
Formula Reactant RPR104952 Product RPR111026
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002568 Cabazitaxel metabolite M07 RPR104952 Oxidation - 10-O-Demethylation Cabazitaxel [1]
MR002562 RP56976 RPR104952 Oxidation - Hydroxylation Cabazitaxel [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002570 Cabazitaxel metabolite M08b RPR111026 Oxidation - 10-O-Demethylation Cabazitaxel [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002564 RPR111026 Cabazitaxel metabolite M09b Oxidation - Hydroxylation Cabazitaxel [1]
MR002565 RPR111026 RPR104943 Oxidation - Hydroxylation Cabazitaxel [1]
References
1 A phase I open-label study investigating the disposition of [14C]-cabazitaxel in patients with advanced solid tumors Anticancer Drugs. 2015 Mar;26(3):350-8. doi: 10.1097/CAD.0000000000000185.

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