Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002592)
Formula
SVG example
8-Hydroxylation
Reactant Carteolol hydrochloride Product 8-hydroxycarteolol
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - 8-Hydroxylation
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002593 8-hydroxycarteolol 5,8-Dihydroxy-3,4-dihydrocarbostyril Unclear Carteolol hydrochloride [1]
MR002591 8-hydroxycarteolol Dihydroxycarteolol Oxidation - Hydroxylation Carteolol hydrochloride [1]
References
1 Involvement of CYP2D1 in the metabolism of carteolol by male rat liver microsomes. Xenobiotica. 1997 Nov;27(11):1121-9.

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