Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002752)
Formula
SVG example
Reactant Prazosin Product 2-(l-Piperazinyl)- 4-amino-6,7 - dimethoxyquinazoline
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002751 Prazosin 2,4-diamino-6,7-dimethoxyquinazoline Unclear Prazosin [1]
MR002753 Prazosin 6-O-demethyl prazosin Oxidation - O-Demethylation Prazosin [2]
MR002754 Prazosin 7-O-demethyl prazosin Oxidation - O-Demethylation Prazosin [2]
MR002748 Prazosin Prazosin metabolite M1 Unclear Prazosin [2]
MR002756 Prazosin Prazosin metabolite M15 Unclear Prazosin [2]
MR002750 Prazosin Prazosin metabolite M16 Unclear Prazosin [2]
MR002755 Prazosin Prazosin metabolite M2 Unclear Prazosin [2]
MR002749 Prazosin Prazosin metabolite M5 Unclear Prazosin [2]
MR002747 Prazosin Prazosin N-glucuronide Conjugation - Glucuronidation Prazosin [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006656 Doxazosin Doxazosin Metabolite M8 Unclear Doxazosin [3]
References
1 DrugBank(Pharmacology-Metabolism)Prazosin
2 Metabolism of prazosin in rat and characterization of metabolites in plasma, urine, faeces, brain and bile using liquid chromatography/mass spectrometry (LC/MS) Xenobiotica. 2008 May;38(5):540-58. doi: 10.1080/00498250802001826.
3 The metabolism and kinetics of doxazosin in man, mouse, rat and dog

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