Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002753)
Formula
SVG example
O-Demethylation
Reactant Prazosin Product 6-O-demethyl prazosin
Reactant Info Product Info
Metabolic Type Oxidation - O-Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002751 Prazosin 2,4-diamino-6,7-dimethoxyquinazoline Unclear Prazosin [1]
MR002752 Prazosin 2-(l-Piperazinyl)- 4-amino-6,7 - dimethoxyquinazoline Unclear Prazosin [1]
MR002754 Prazosin 7-O-demethyl prazosin Oxidation - O-Demethylation Prazosin [2]
MR002748 Prazosin Prazosin metabolite M1 Unclear Prazosin [2]
MR002756 Prazosin Prazosin metabolite M15 Unclear Prazosin [2]
MR002750 Prazosin Prazosin metabolite M16 Unclear Prazosin [2]
MR002755 Prazosin Prazosin metabolite M2 Unclear Prazosin [2]
MR002749 Prazosin Prazosin metabolite M5 Unclear Prazosin [2]
MR002747 Prazosin Prazosin N-glucuronide Conjugation - Glucuronidation Prazosin [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002739 6-O-demethyl prazosin Prazosin 6-O-glucuronide Conjugation - Glucuronidation Prazosin [2]
References
1 DrugBank(Pharmacology-Metabolism)Prazosin
2 Metabolism of prazosin in rat and characterization of metabolites in plasma, urine, faeces, brain and bile using liquid chromatography/mass spectrometry (LC/MS) Xenobiotica. 2008 May;38(5):540-58. doi: 10.1080/00498250802001826.

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