Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002808)
Formula
SVG example
Oxidation
Reactant Calcifediol Product 20(S),25-dihydroxyvitamin D3
Reactant Info Product Info
Metabolic Enzyme Cholesterol desmolase (CYP11A1) DME Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002811 Calcifediol 1,25(OH)2D3-23,26-lactone Unclear Calcifediol [1]
MR002810 Calcifediol 25(OH)D3-23,26 lactone Unclear Calcifediol [1]
MR002812 Calcifediol Calcitriol Oxidation - 25-Hydroxylation Calcifediol [2]
MR002809 Calcifediol Secalciferol Unclear Calcifediol [1]
References
1 Synthesis of Deuterium-Labeled Vitamin D Metabolites as Internal Standards for LC-MS Analysis Molecules. 2022 Apr 9;27(8):2427. doi: 10.3390/molecules27082427.
2 Cytochromes P450 are essential players in the vitamin D signaling system. Biochim Biophys Acta. 2011 Jan;1814(1):186-99.

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