Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002809)
Formula
SVG example
Reactant Calcifediol Product Secalciferol
Reactant Info Product Info
Metabolic Enzyme Vitamin D(3) 24-hydroxylase (CYP24A1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002811 Calcifediol 1,25(OH)2D3-23,26-lactone Unclear Calcifediol [1]
MR002808 Calcifediol 20(S),25-dihydroxyvitamin D3 Oxidation - Oxidation Calcifediol [1]
MR002810 Calcifediol 25(OH)D3-23,26 lactone Unclear Calcifediol [1]
MR002812 Calcifediol Calcitriol Oxidation - 25-Hydroxylation Calcifediol [2]
References
1 Synthesis of Deuterium-Labeled Vitamin D Metabolites as Internal Standards for LC-MS Analysis Molecules. 2022 Apr 9;27(8):2427. doi: 10.3390/molecules27082427.
2 Cytochromes P450 are essential players in the vitamin D signaling system. Biochim Biophys Acta. 2011 Jan;1814(1):186-99.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.