Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002998)
Formula
CYP24A1 ...
SVG example
Unclear
Reactant 25-hydroxyvitamin D Product Calcitro
Reactant Info Product Info
Metabolic Enzyme Vitamin D(3) 24-hydroxylase (CYP24A1) DME Info
Calcidiol 1-monooxygenase (CYP27B1) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002997 Ergocalciferol 25-hydroxyvitamin D Unclear - Unclear Ergocalciferol [1], [2], [3]
References
1 Vitamin D: mechanisms of action and clinical applications. Endocrinol Metab Clin North Am. 2017 Dec;46(4):xvii-xviii.
2 Characterization of rat and human CYP2J enzymes as Vitamin D 25-hydroxylases. Steroids. 2006 Oct;71(10):849-56.
3 CYP2R1 (vitamin D 25-hydroxylase) gene is associated with susceptibility to type 1 diabetes and vitamin D levels in Germans. Diabetes Metab Res Rev. 2007 Nov;23(8):631-6.

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